Abstract: The advent of atomically thin materials brings out innovative paradigms, examining the intricate relationships among charge, spin, lattice, valley, and photons. Particularly striking are the quantum effects observed when layering twodimensional (2D) materials. A notable example is the pioneering study demonstrating that two graphene layers twisted at specific "magic" angles can exhibit insulating or superconductivity. This approach paves the way to developing artificial 2D hybrid quantum materials that merge various 2D materials deliberately, unlocking groundbreaking functions and expanding the horizon of quantum materials. In my talk, I will share our latest advances in crafting artificial 2D hybrid materials with meticulous control over twist angles and strain. We integrate the 2D materials stacking technologies with a handful of optical spectroscopy, including second harmonic generation, absorption, photoluminescence, and Raman spectroscopy. Our homemade system can facilitate in-situ monitoring and precisely controls strain and twist-angle. Our research is a stepping stone toward realizing the full potential of 2D materials, potentially leading to breakthroughs in quantum computing, exciton physics, and other emergent fields.